The preparation of non-sterile extemporaneous cytotoxic suspensions

Dissolution Stability Study of Cefadroxil Extemporaneous Suspensions

Dissolution studies have become matter of great significance because, in most cases, drug dissolution is the rate-limiting step in the absorption process. As occurs with solid oral dosage forms, heterogeneous disperse systems (suspensions) could also have some problems with their in vitro dissolution. The dissolution behavior of four different brands of cefadroxil extemporaneous suspensions ava...

Vibration of Road Vehicles with Non linear Suspensions

In order to investigate the effects of non-linear springs in vibrating behavior of vehicles, the independent suspension of conventional vehicles could be modeled as a non-linear single degree of freedom system. The equation of motion for the system would be a non-linear third order ordinary differential equation, when considering the elasticity of rubber bushings in joints of shock absorber. It...

Extemporaneous clobazam suspensions for paediatric use prepared from commercially available tablets and pure drug.

OBJECTIVE Two clobazam aqueous suspensions for paediatric oral usage (5 mg/ml) were investigated to determinate its physicochemical stability under different storage conditions. METHOD Formulations were stored at 4 and 25 °C and the clobazam content was determined by High Performance Liquid Chromatography. Each sample was analyzed by triplicate at different time points (0, 7, 14, 28 and 56 da...

Extemporaneous Furosemide Suspensions for Pediatrics Use Prepared from Commercially Available Tablets

Objective: Three furosemide aqueous suspensions for paediatric oral usage (2 mg/ml) were investigated to determinate its physicochemical stability under different storage conditions. Method: Formulations using sugar syrup and sugar-free vehicles were stored at 4 and 25 o C and the furosemide content was determined by spectrophotometer. Each sample was analyzed in triplicate at different time po...

Sterile & Non Sterile Manufacturing Operation Manuals